Page 6 - Baking Europe - Summer 2016 Issue
P. 6


A pilot study of Baker’s yeast
as a potential contributor to
the obesity complex

Applying immunological techniques the antibodies against Baker’s yeast were measured in 58 obese
and normal weight individuals in Central Norway

S. Salamati1, C. Martins1,2 and B. E. Kulseng1,2

Introduction                        and a sedentary life style are       growth promoters (AGP) in feed
Obesity is now one of the           considered as major causes, the      industry. AGPs were banned in the
major health issues worldwide.      involvement of environmental         EU in 2006 (2). The mode of action
The population of overweight        factors should not be overseen.      of these low-dosage antibiotics
individuals has more than           Baker’s yeast (Saccharomyces         in simple terms would be the
doubled since 1980 to an            cerevisiae) itself or its cell wall  reduction of bacterial load in the
approximately 1.9 billion in 2014.  products (β-glucan and mannan        gastrointestinal tract (GIT) and
Of these 600 million were obese     oligosaccharides) are now used as    giving rise to an effective energy
(1). Though energy dense food       one the alternatives to antibiotic   uptake. Hundreds of papers
                                                                         on the effect of Baker’s yeast
                                                                         and its products show similar
                                                                         effects on growth promotion in
                                                                         food animals (3). Yeast culture
                                                                         is a natural fermentation
                                                                         product containing yeast cell
                                                                         wall (containing beta-glucans
                                                                         and mannan-oligosaccharides),
                                                                         cell solubles, B vitamins,
                                                                         proteins, peptides, amino acids,
                                                                         nucleotides, lipids, organic acids,
                                                                         esters, and alcohols (4,5). These
                                                                         products which more or less exist
                                                                         in any culture of Baker’s yeast
                                                                         can give rise to excess energy.
                                                                         This gave us the interest to look
                                                                         deeper into this food component
                                                                         in relation to human obesity.

                                                                         Anti-Saccharomyces cerevisiae
                                                                         antibodies (ASCA) were
                                                                         traditionally used in the
                                                                         study of Crohn’s disease. We

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